Neuroendocrinology and Traumatic Brain Injury

Symposium

Special Topics

Mon, 6/13, 2:00 PM
Columbia Hall 8

• Brent Masel, MD
  Transitional Learning Center, Galveston
  bmasel@tlc-galveston.org
• David L. Ripley, MD
  CNS Medical Group, Craig Hospital
  dripley@craighospital.org
• Donald Stein, PhD
  Emory University
  dstei04@emory.edu

• Participants will understand the basic science background of neuroendocrine dysfunction after traumatic brain injury and the potential clinical implications of this dysfunction.
• Participants will be updated on completed and ongoing clinical trials on neuroendocrine dysfunction and hormone therapy after brain injury.

Recent studies have demonstrated the importance of neuroendocrine disorders and their potential impact on recovery after traumatic brain injury. These studies suggest that dysfunction of various endocrine pathways is extremely common, occurring in 50% or more of TBI survivors. Additionally, most studies suggest that there is poor correlation between severity of injury and the presence of these abnormalities. Several clinical trials are currently underway to investigate the efficacy of hormone replacement therapy for dysfunction of various hormone systems. This symposium will review the basic science background for the importance of this area, and discuss several clinical trials that have been completed or are underway on hormone therapy after TBI.